Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
efeU_1Iron permease FTR1 family protein; [P] COG0672 High-affinity Fe2+/Pb2+ permease. (286 aa)    
Predicted Functional Partners:
efeO
Imelysin family protein; [P] COG2822 Predicted periplasmic lipoprotein involved in iron transport.
  
 0.999
efeB
Dyp-type peroxidase family protein; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Belongs to the DyP-type peroxidase family.
 
  
 0.981
tpd
Fe2+ transport family protein; [P] COG3470 Uncharacterized protein probably involved in high-affinity Fe2+ transport.
 
  
 0.709
fcuA_2
tonB-siderophor: TonB-dependent siderophore receptor family protein; [P] COG1629 Outer membrane receptor proteins, mostly Fe transport.
   
    0.534
CH54_3161
tonB-siderophor: TonB-dependent siderophore receptor family protein; [P] COG1629 Outer membrane receptor proteins, mostly Fe transport.
   
    0.534
efeU_2
Iron permease FTR1 family protein; [P] COG0672 High-affinity Fe2+/Pb2+ permease.
  
  
 
0.521
yfeX
Dyp_perox_fam: Dyp-type peroxidase family protein; [P] COG2837 Predicted iron-dependent peroxidase.
  
  
 0.517
putP
Sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
       0.470
CH54_707
YHS domain protein; [S] COG4393 Predicted membrane protein.
 
  
 0.467
CH54_3872
[G] COG4580 Maltoporin (phage lambda and maltose receptor).
  
     0.455
Your Current Organism:
Yersinia kristensenii
NCBI taxonomy Id: 28152
Other names: ATCC 33638, CCUG 11294, CCUG 8241, CIP 80.30, DSM 18543, JCM 7576, NCTC 11471, Y. kristensenii, strain 105
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