close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cbiG[H] COG2073 Cobalamin biosynthesis protein CbiG. (370 aa)    
Predicted Functional Partners:
cobJ
cobJ_cbiH: precorrin-3B C17-methyltransferase; [H] COG1010 Precorrin-3B methylase.
  
 0.999
cobM
cobM_cbiF: precorrin-4 C11-methyltransferase; [H] COG2875 Precorrin-4 methylase.
 
 0.999
cbiD
Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
 
 0.999
cobK
Precor6x_red: precorrin-6x reductase; [H] COG2099 Precorrin-6x reductase.
  
 0.994
cobI
cobI_cbiL: precorrin-2 C(20)-methyltransferase; [H] COG2243 Precorrin-2 methylase; Belongs to the precorrin methyltransferase family.
 
  
 0.993
cbiC
precorrin-8X methylmutase family protein; [H] COG2082 Precorrin isomerase.
 
  
 0.992
cbiK
cbiX family protein; Catalyzes the insertion of Co(2+) into sirohydrochlorin. Belongs to the CbiK family.
 
  
 0.991
cobB
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
  
 0.973
cbiT
cbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; [H] COG2242 Precorrin-6B methylase 2.
 
  
 0.972
cbiE
cbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; [H] COG2241 Precorrin-6B methylase 1.
 
  
 0.972
Your Current Organism:
Yersinia kristensenii
NCBI taxonomy Id: 28152
Other names: ATCC 33638, CCUG 11294, CCUG 8241, CIP 80.30, DSM 18543, JCM 7576, NCTC 11471, Y. kristensenii, strain 105
Server load: low (24%) [HD]