STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bglX1Hypothetical protein; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. (341 aa)    
Predicted Functional Partners:
chb
Glycosyl hydrolase family 20, catalytic domain protein; [G] COG3525 N-acetyl-beta-hexosaminidase.
    
 0.925
CH54_3098
Hypothetical protein; Glycosyl hydrolase family 3 N terminal domain protein; [G] COG1472 Beta-glucosidase-related glycosidases.
  
  
 
0.924
nagK
Glucokinase family protein; Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.
    
 0.901
CH54_99
Conserved hypothetical protein; [R] COG3150 Predicted esterase; Belongs to the UPF0227 family.
  
    0.807
anmK
Hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.
 
  
 0.772
ampD
N-acetylmuramoyl-L-alanine amidase family protein; [V] COG3023 Negative regulator of beta-lactamase expression.
 
  
 0.752
amiB
[M] COG0860 N-acetylmuramoyl-L-alanine amidase.
    
 0.706
thiK
ycfN_thiK: thiamine kinase; [M] COG0510 Predicted choline kinase involved in LPS biosynthesis.
  
    0.697
lpoB
Hypothetical protein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b). Belongs to the LpoB family.
  
    0.694
ycfL
Conserved hypothetical protein; [R] COG5633 Predicted periplasmic lipoprotein.
       0.642
Your Current Organism:
Yersinia kristensenii
NCBI taxonomy Id: 28152
Other names: ATCC 33638, CCUG 11294, CCUG 8241, CIP 80.30, DSM 18543, JCM 7576, NCTC 11471, Y. kristensenii, strain 105
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