STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A2H2HYH3MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (426 aa)    
Predicted Functional Partners:
A0A2H2ICM6
AP-1 complex subunit gamma.
   
 0.999
K7GX73_CAEJA
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 0.999
A0A2H2IIY9
Uncharacterized protein.
    
 0.984
K7GXM2_CAEJA
AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
   
 0.966
A0A2H2IL81
Uncharacterized protein.
    
 
 0.960
A0A2H2IF32
Adaptin_N domain-containing protein.
   
 0.951
A0A2H2III7
MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.
  
  
 
0.950
K7I0B0_CAEJA
B2-adapt-app_C domain-containing protein.
    
 0.940
A0A2H2J179
Importin N-terminal domain-containing protein.
   
 
 0.936
K7H1A3_CAEJA
CRM1_C domain-containing protein.
   
 
 0.936
Your Current Organism:
Caenorhabditis japonica
NCBI taxonomy Id: 281687
Other names: C. japonica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.