STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
asna-1ATPase asna-1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] (348 aa)    
Predicted Functional Partners:
K7H4R7_CAEJA
Uncharacterized protein.
    
 0.989
A0A2H2I3P3
Uncharacterized protein.
   
 0.983
A0A2H2HZB6
Uncharacterized protein.
   
 0.943
A0A2H2I5G7
t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family.
   
 0.907
A0A2H2IC68
TPR_REGION domain-containing protein.
   
 0.871
A0A2H2HXZ6
Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.
    
 0.785
K7HRY4_CAEJA
Uncharacterized protein.
    
 0.785
A0A2Q4SNX0
Ubiquitin-like domain-containing protein.
   
 0.782
A0A2H2I8U0
UBA domain-containing protein.
   
 0.780
A0A2H2HWY7
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
    
 0.764
Your Current Organism:
Caenorhabditis japonica
NCBI taxonomy Id: 281687
Other names: C. japonica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.