STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A2H2JAV6Histone H2A; Belongs to the histone H2A family. (144 aa)    
Predicted Functional Partners:
K7H6M1_CAEJA
Uncharacterized protein.
    
 0.972
A0A2H2I513
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 0.946
A0A2Q4SHJ1
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 0.944
A0A2H2INR3
Histone H2A; Belongs to the histone H2A family.
  
0.939
A0A2H2IH19
Ubiquitin-like domain-containing protein.
    
 0.924
A0A2H2I3C6
Uncharacterized protein.
   
 0.905
A0A2H2HUB1
BRCT domain-containing protein.
    
 0.904
A0A2H2I985
Uncharacterized protein.
    
 0.898
A0A2H2IC89
DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.
    
  0.892
A0A2H2IH01
WD_REPEATS_REGION domain-containing protein.
    
 0.890
Your Current Organism:
Caenorhabditis japonica
NCBI taxonomy Id: 281687
Other names: C. japonica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.