STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trxCThioredoxin-2; Function of homologous gene experimentally demonstrated in an other organism; carrier. (144 aa)    
Predicted Functional Partners:
trxB
Thioredoxin reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.797
CCO60881.1
Putative Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
     
 0.665
CCO60882.1
Putative TWO COMPONENT HISTIDINE KINASE; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
       0.661
CCO60883.1
Putative ABC-type Fe3+ transport system, periplasmic component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
       0.661
groL
60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 
 0.594
grpE
Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
 
  
 0.559
CCO58442.1
Putative low molecular weight protein-tyrosine-phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
 
 0.553
CCO60738.1
Putative Protein-tyrosine phosphatase, low molecular weight; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.553
Prdx2
Peroxiredoxin-2; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.551
CCO59561.1
Hybrid peroxiredoxin hyPrx5; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 
 0.547
Your Current Organism:
Vibrio nigripulchritudo
NCBI taxonomy Id: 28173
Other names: ATCC 27043, Beneckea nigrapulchrituda, Beneckea nigripulchritudo, CAIM 323, CCUG 28586, CIP 103195, LMG 3896, LMG:3896, V. nigripulchritudo
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.