dnaK protein (Photodesmus katoptron) - STRING interaction network

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Score

dnaK

Chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. (667 aa)

Predicted Functional Partners:

dnaL

0.999

grpE

0.991

htpG

0.990

clpB

0.949

clpA

0.943

groL1

0.935

rplP

0.922

iscU

0.920

hscB

0.894

groS

0.843

Your Current Organism:

Photodesmus katoptron

NCBI taxonomy Id: 28176
Other names: Anomalops katoptron symbiont, C. Photodesmus katoptron, Candidatus Photodesmus katoptron

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
clpA	dnaK	CF66_2168	CF66_0102	ATP-dependent Clp protease ATP-binding subunit; Belongs to the ClpA/ClpB family.	Chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.943
clpA	dnaL	CF66_2168	CF66_0103	ATP-dependent Clp protease ATP-binding subunit; Belongs to the ClpA/ClpB family.	Chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK a [...]	0.835
clpA	groL1	CF66_2168	CF66_2083	ATP-dependent Clp protease ATP-binding subunit; Belongs to the ClpA/ClpB family.	60 kDa chaperonin 1; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.614
clpA	groS	CF66_2168	CF66_2082	ATP-dependent Clp protease ATP-binding subunit; Belongs to the ClpA/ClpB family.	10 kDa chaperonin; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.	0.610
clpA	grpE	CF66_2168	CF66_0101	ATP-dependent Clp protease ATP-binding subunit; Belongs to the ClpA/ClpB family.	Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depen [...]	0.797
clpA	htpG	CF66_2168	CF66_2170	ATP-dependent Clp protease ATP-binding subunit; Belongs to the ClpA/ClpB family.	Chaperone protein; Molecular chaperone. Has ATPase activity.	0.668
clpB	dnaK	CF66_9028	CF66_0102	Chaperone protein ClpB; Belongs to the ClpA/ClpB family.	Chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.949
clpB	dnaL	CF66_9028	CF66_0103	Chaperone protein ClpB; Belongs to the ClpA/ClpB family.	Chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK a [...]	0.835
clpB	groL1	CF66_9028	CF66_2083	Chaperone protein ClpB; Belongs to the ClpA/ClpB family.	60 kDa chaperonin 1; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.645
clpB	groS	CF66_9028	CF66_2082	Chaperone protein ClpB; Belongs to the ClpA/ClpB family.	10 kDa chaperonin; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.	0.622
clpB	grpE	CF66_9028	CF66_0101	Chaperone protein ClpB; Belongs to the ClpA/ClpB family.	Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depen [...]	0.804
clpB	htpG	CF66_9028	CF66_2170	Chaperone protein ClpB; Belongs to the ClpA/ClpB family.	Chaperone protein; Molecular chaperone. Has ATPase activity.	0.679
dnaK	clpA	CF66_0102	CF66_2168	Chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.	ATP-dependent Clp protease ATP-binding subunit; Belongs to the ClpA/ClpB family.	0.943
dnaK	clpB	CF66_0102	CF66_9028	Chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Chaperone protein ClpB; Belongs to the ClpA/ClpB family.	0.949
dnaK	dnaL	CF66_0102	CF66_0103	Chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK a [...]	0.999
dnaK	groL1	CF66_0102	CF66_2083	Chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.	60 kDa chaperonin 1; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.935
dnaK	groS	CF66_0102	CF66_2082	Chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.	10 kDa chaperonin; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.	0.843
dnaK	grpE	CF66_0102	CF66_0101	Chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depen [...]	0.991
dnaK	hscB	CF66_0102	CF66_9022	Chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Co-chaperone protein; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.	0.894
dnaK	htpG	CF66_0102	CF66_2170	Chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Chaperone protein; Molecular chaperone. Has ATPase activity.	0.990