| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| carA | purC | CF66_2249 | CF66_2280 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.598 |
| carA | purD | CF66_2249 | CF66_2409 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | 0.597 |
| carA | purE | CF66_2249 | CF66_1203 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.613 |
| carA | purF | CF66_2249 | CF66_7110 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.782 |
| carA | purH | CF66_2249 | CF66_2410 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Bifunctional purine biosynthesis protein. | 0.841 |
| carA | purK | CF66_2249 | CF66_1204 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.523 |
| carA | purL | CF66_2249 | CF66_0105 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.992 |
| carA | purM | CF66_2249 | CF66_3049 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Phosphoribosylformylglycinamidine cycloligase. | 0.590 |
| purB | purC | CF66_7097 | CF66_2280 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.988 |
| purB | purD | CF66_7097 | CF66_2409 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | 0.973 |
| purB | purE | CF66_7097 | CF66_1203 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.964 |
| purB | purF | CF66_7097 | CF66_7110 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.958 |
| purB | purH | CF66_7097 | CF66_2410 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Bifunctional purine biosynthesis protein. | 0.985 |
| purB | purK | CF66_7097 | CF66_1204 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.940 |
| purB | purL | CF66_7097 | CF66_0105 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.999 |
| purB | purM | CF66_7097 | CF66_3049 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine cycloligase. | 0.924 |
| purB | purN | CF66_7097 | CF66_3048 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.951 |
| purC | carA | CF66_2280 | CF66_2249 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | 0.598 |
| purC | purB | CF66_2280 | CF66_7097 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.988 |
| purC | purD | CF66_2280 | CF66_2409 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | 0.991 |