| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CF66_0115 | CF66_0116 | CF66_0115 | CF66_0116 | Membrane protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Membrane protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.998 |
| CF66_0115 | copA | CF66_0115 | CF66_2086 | Membrane protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Copper-translocating P-type ATPase. | 0.508 |
| CF66_0115 | glyA | CF66_0115 | CF66_0117 | Membrane protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.436 |
| CF66_0115 | tolC | CF66_0115 | CF66_2154 | Membrane protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Outer membrane protein. | 0.977 |
| CF66_0116 | CF66_0115 | CF66_0116 | CF66_0115 | Membrane protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | Membrane protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.998 |
| CF66_0116 | CF66_2423 | CF66_0116 | CF66_2423 | Membrane protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | Signaling protein. | 0.488 |
| CF66_0116 | copA | CF66_0116 | CF66_2086 | Membrane protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | Copper-translocating P-type ATPase. | 0.406 |
| CF66_0116 | glyA | CF66_0116 | CF66_0117 | Membrane protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.464 |
| CF66_0116 | secD | CF66_0116 | CF66_4057 | Membrane protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | Protein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.445 |
| CF66_0116 | secF | CF66_0116 | CF66_4058 | Membrane protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | Protein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.441 |
| CF66_0116 | tolC | CF66_0116 | CF66_2154 | Membrane protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | Outer membrane protein. | 0.967 |
| CF66_0116 | yajC | CF66_0116 | CF66_4056 | Membrane protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | Membrane protein yajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. | 0.832 |
| CF66_2423 | CF66_0116 | CF66_2423 | CF66_0116 | Signaling protein. | Membrane protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.488 |
| CF66_2423 | tolC | CF66_2423 | CF66_2154 | Signaling protein. | Outer membrane protein. | 0.457 |
| copA | CF66_0115 | CF66_2086 | CF66_0115 | Copper-translocating P-type ATPase. | Membrane protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.508 |
| copA | CF66_0116 | CF66_2086 | CF66_0116 | Copper-translocating P-type ATPase. | Membrane protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.406 |
| copA | tolC | CF66_2086 | CF66_2154 | Copper-translocating P-type ATPase. | Outer membrane protein. | 0.605 |
| glyA | CF66_0115 | CF66_0117 | CF66_0115 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Membrane protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.436 |
| glyA | CF66_0116 | CF66_0117 | CF66_0116 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Membrane protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.464 |
| secD | CF66_0116 | CF66_4057 | CF66_0116 | Protein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | Membrane protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.445 |