| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CF66_2010 | cdsA | CF66_2010 | CF66_2008 | Zinc metalloprotease. | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | 0.866 |
| CF66_2010 | dxr | CF66_2010 | CF66_2009 | Zinc metalloprotease. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.863 |
| CF66_2010 | fabZ | CF66_2010 | CF66_2015 | Zinc metalloprotease. | (3R)-hydroxymyristoyl-acyl-carrier-protein dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.558 |
| CF66_2010 | frr | CF66_2010 | CF66_2006 | Zinc metalloprotease. | Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.558 |
| CF66_2010 | ipxD | CF66_2010 | CF66_2014 | Zinc metalloprotease. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.711 |
| CF66_2010 | pyrH | CF66_2010 | CF66_2005 | Zinc metalloprotease. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.580 |
| CF66_2010 | skp | CF66_2010 | CF66_2012 | Zinc metalloprotease. | Chaperone protein. | 0.796 |
| CF66_2010 | topA | CF66_2010 | CF66_0170 | Zinc metalloprotease. | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.538 |
| CF66_2010 | uppS | CF66_2010 | CF66_2007 | Zinc metalloprotease. | Undecaprenyl pyrophosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.890 |
| CF66_2010 | yaeT | CF66_2010 | CF66_2011 | Zinc metalloprotease. | Outer membrane protein assembly factor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.947 |
| cdsA | CF66_2010 | CF66_2008 | CF66_2010 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | Zinc metalloprotease. | 0.866 |
| cdsA | dxr | CF66_2008 | CF66_2009 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.874 |
| cdsA | fabZ | CF66_2008 | CF66_2015 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | (3R)-hydroxymyristoyl-acyl-carrier-protein dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.449 |
| cdsA | frr | CF66_2008 | CF66_2006 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.675 |
| cdsA | ipxD | CF66_2008 | CF66_2014 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.606 |
| cdsA | pyrH | CF66_2008 | CF66_2005 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.675 |
| cdsA | skp | CF66_2008 | CF66_2012 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | Chaperone protein. | 0.637 |
| cdsA | uppS | CF66_2008 | CF66_2007 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | Undecaprenyl pyrophosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.980 |
| cdsA | yaeT | CF66_2008 | CF66_2011 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | Outer membrane protein assembly factor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.614 |
| dxr | CF66_2010 | CF66_2009 | CF66_2010 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Zinc metalloprotease. | 0.863 |