| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CF66_2353 | ccmH | CF66_2353 | CF66_2276 | Membrane protein. | Cytochrome c-type biogenesis protein H. | 0.579 |
| CF66_2353 | holA | CF66_2353 | CF66_0125 | Membrane protein. | DNA polymerase III subunit delta. | 0.620 |
| CF66_2353 | ypjD | CF66_2353 | CF66_2098 | Membrane protein. | Inner membrane protein. | 0.509 |
| CF66_2353 | zapB | CF66_2353 | CF66_2088 | Membrane protein. | Cell division protein; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. | 0.769 |
| ccmH | CF66_2353 | CF66_2276 | CF66_2353 | Cytochrome c-type biogenesis protein H. | Membrane protein. | 0.579 |
| ccmH | smg | CF66_2276 | CF66_3030 | Cytochrome c-type biogenesis protein H. | Protein smg; Belongs to the Smg family. | 0.469 |
| ccmH | ypjD | CF66_2276 | CF66_2098 | Cytochrome c-type biogenesis protein H. | Inner membrane protein. | 0.502 |
| ccmH | zapB | CF66_2276 | CF66_2088 | Cytochrome c-type biogenesis protein H. | Cell division protein; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. | 0.674 |
| ffh | rimM | CF66_2097 | CF66_2095 | Signal recognition particle GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual component [...] | Ribosome maturation factor; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. | 0.698 |
| ffh | rpsP | CF66_2097 | CF66_2096 | Signal recognition particle GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual component [...] | 30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. | 0.938 |
| ffh | trmD | CF66_2097 | CF66_2094 | Signal recognition particle GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual component [...] | tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | 0.737 |
| ffh | yfjD | CF66_2097 | CF66_2099 | Signal recognition particle GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual component [...] | Inner membrane protein. | 0.606 |
| ffh | ypjD | CF66_2097 | CF66_2098 | Signal recognition particle GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual component [...] | Inner membrane protein. | 0.698 |
| holA | CF66_2353 | CF66_0125 | CF66_2353 | DNA polymerase III subunit delta. | Membrane protein. | 0.620 |
| holA | ypjD | CF66_0125 | CF66_2098 | DNA polymerase III subunit delta. | Inner membrane protein. | 0.548 |
| holA | zapB | CF66_0125 | CF66_2088 | DNA polymerase III subunit delta. | Cell division protein; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. | 0.463 |
| rimM | ffh | CF66_2095 | CF66_2097 | Ribosome maturation factor; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. | Signal recognition particle GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual component [...] | 0.698 |
| rimM | rpsP | CF66_2095 | CF66_2096 | Ribosome maturation factor; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. | 30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. | 0.993 |
| rimM | trmD | CF66_2095 | CF66_2094 | Ribosome maturation factor; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. | tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | 0.993 |
| rimM | yfjD | CF66_2095 | CF66_2099 | Ribosome maturation factor; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. | Inner membrane protein. | 0.547 |