Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gltACitrate synthase; Belongs to the citrate synthase family. (423 aa)    
Predicted Functional Partners:
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
  
 0.998
fumB
Fumarate hydratase class I, anaerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.993
acnB
Aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family.
  
 
 0.992
aceF
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.
  
 0.988
sucA
2-oxoglutarate dehydrogenase E1 component.
  
 0.985
sucC
succinyl-CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 0.974
sdhA
Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
  
 0.964
atoB
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.961
gdhB
NAD-specific glutamate dehydrogenase.
     
 0.957
sdhB
Succinate dehydrogenase iron-sulfur subunit.
  
 0.951
Your Current Organism:
Photodesmus katoptron
NCBI taxonomy Id: 28176
Other names: Anomalops katoptron symbiont, C. Photodesmus katoptron, Candidatus Photodesmus katoptron
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.