| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aceF | fumB | CF66_2077 | CF66_2369 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex. | Fumarate hydratase class I, anaerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.468 |
| aceF | gltA | CF66_2077 | CF66_2308 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex. | Citrate synthase; Belongs to the citrate synthase family. | 0.850 |
| aceF | sdhA | CF66_2077 | CF66_2311 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex. | Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.683 |
| aceF | sdhB | CF66_2077 | CF66_2312 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex. | Succinate dehydrogenase iron-sulfur subunit. | 0.771 |
| aceF | sucA | CF66_2077 | CF66_2313 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex. | 2-oxoglutarate dehydrogenase E1 component. | 0.994 |
| aceF | sucC | CF66_2077 | CF66_2315 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex. | succinyl-CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.906 |
| aceF | sucD | CF66_2077 | CF66_2316 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex. | succinyl-CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.859 |
| fumB | aceF | CF66_2369 | CF66_2077 | Fumarate hydratase class I, anaerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex. | 0.468 |
| fumB | gltA | CF66_2369 | CF66_2308 | Fumarate hydratase class I, anaerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Citrate synthase; Belongs to the citrate synthase family. | 0.971 |
| fumB | sdhA | CF66_2369 | CF66_2311 | Fumarate hydratase class I, anaerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.997 |
| fumB | sdhB | CF66_2369 | CF66_2312 | Fumarate hydratase class I, anaerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Succinate dehydrogenase iron-sulfur subunit. | 0.979 |
| fumB | sdhC | CF66_2369 | CF66_2309 | Fumarate hydratase class I, anaerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Succinate dehydrogenase cytochrome b556 subunit. | 0.958 |
| fumB | sdhD | CF66_2369 | CF66_2310 | Fumarate hydratase class I, anaerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Succinate dehydrogenase hydrophobic membrane anchor subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH). | 0.958 |
| fumB | sucA | CF66_2369 | CF66_2313 | Fumarate hydratase class I, anaerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 2-oxoglutarate dehydrogenase E1 component. | 0.751 |
| fumB | sucB | CF66_2369 | CF66_2314 | Fumarate hydratase class I, anaerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex. | 0.468 |
| fumB | sucC | CF66_2369 | CF66_2315 | Fumarate hydratase class I, anaerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | succinyl-CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.936 |
| fumB | sucD | CF66_2369 | CF66_2316 | Fumarate hydratase class I, anaerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | succinyl-CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.915 |
| gltA | aceF | CF66_2308 | CF66_2077 | Citrate synthase; Belongs to the citrate synthase family. | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex. | 0.850 |
| gltA | fumB | CF66_2308 | CF66_2369 | Citrate synthase; Belongs to the citrate synthase family. | Fumarate hydratase class I, anaerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.971 |
| gltA | sdhA | CF66_2308 | CF66_2311 | Citrate synthase; Belongs to the citrate synthase family. | Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.958 |