| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| carA | carB | CF66_2249 | CF66_2250 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | 0.999 |
| carA | fre | CF66_2249 | CF66_3036 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | NAD(P)H-flavin reductase. | 0.834 |
| carA | guaA | CF66_2249 | CF66_9008 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.513 |
| carA | guaB | CF66_2249 | CF66_9009 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.745 |
| carA | luxG | CF66_2249 | CF66_3017 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Flavin reductase luxG. | 0.834 |
| carA | pyrB | CF66_2249 | CF66_3023 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
| carA | pyrC | CF66_2249 | CF66_7103 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. | 0.700 |
| carA | pyrD | CF66_2249 | CF66_2379 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.929 |
| carA | pyrE | CF66_2249 | CF66_3011 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.920 |
| carA | pyrF | CF66_2249 | CF66_2355 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Rotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.921 |
| carB | carA | CF66_2250 | CF66_2249 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | 0.999 |
| carB | fre | CF66_2250 | CF66_3036 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | NAD(P)H-flavin reductase. | 0.843 |
| carB | guaA | CF66_2250 | CF66_9008 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.900 |
| carB | guaB | CF66_2250 | CF66_9009 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.850 |
| carB | luxG | CF66_2250 | CF66_3017 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Flavin reductase luxG. | 0.843 |
| carB | pyrB | CF66_2250 | CF66_3023 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
| carB | pyrC | CF66_2250 | CF66_7103 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. | 0.711 |
| carB | pyrD | CF66_2250 | CF66_2379 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.979 |
| carB | pyrE | CF66_2250 | CF66_3011 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.972 |
| carB | pyrF | CF66_2250 | CF66_2355 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Rotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.951 |