| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| birA | folB | CF66_2125 | CF66_2204 | Bifunctional protein. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.636 |
| birA | folC | CF66_2125 | CF66_7113 | Bifunctional protein. | Bifunctional protein folC; Belongs to the folylpolyglutamate synthase family. | 0.457 |
| birA | folE | CF66_2125 | CF66_2385 | Bifunctional protein. | GTP cyclohydrolase 1. | 0.461 |
| birA | folK | CF66_2125 | CF66_5006 | Bifunctional protein. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 0.705 |
| birA | folP | CF66_2125 | CF66_2117 | Bifunctional protein. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.637 |
| birA | pabC | CF66_2125 | CF66_2335 | Bifunctional protein. | Aminodeoxychorismate lyase. | 0.494 |
| birA | panC | CF66_2125 | CF66_5007 | Bifunctional protein. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.805 |
| birA | pcnB | CF66_2125 | CF66_5005 | Bifunctional protein. | poly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | 0.849 |
| birA | ribB | CF66_2125 | CF66_4065 | Bifunctional protein. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.633 |
| birA | ribD | CF66_2125 | CF66_4064 | Bifunctional protein. | Riboflavin biosynthesis protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.652 |
| folB | birA | CF66_2204 | CF66_2125 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Bifunctional protein. | 0.636 |
| folB | folC | CF66_2204 | CF66_7113 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Bifunctional protein folC; Belongs to the folylpolyglutamate synthase family. | 0.753 |
| folB | folE | CF66_2204 | CF66_2385 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | GTP cyclohydrolase 1. | 0.967 |
| folB | folK | CF66_2204 | CF66_5006 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 0.984 |
| folB | folP | CF66_2204 | CF66_2117 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.967 |
| folB | pabC | CF66_2204 | CF66_2335 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Aminodeoxychorismate lyase. | 0.510 |
| folB | ribB | CF66_2204 | CF66_4065 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.480 |
| folB | ribD | CF66_2204 | CF66_4064 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Riboflavin biosynthesis protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.642 |
| folC | birA | CF66_7113 | CF66_2125 | Bifunctional protein folC; Belongs to the folylpolyglutamate synthase family. | Bifunctional protein. | 0.457 |
| folC | folB | CF66_7113 | CF66_2204 | Bifunctional protein folC; Belongs to the folylpolyglutamate synthase family. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.753 |