| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CF66_7028 | mutY | CF66_7028 | CF66_7027 | Fe(2+)-trafficking protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.735 |
| CF66_7028 | trmB | CF66_7028 | CF66_7026 | Fe(2+)-trafficking protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.521 |
| birA | mutY | CF66_2125 | CF66_7027 | Bifunctional protein. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.586 |
| birA | trmB | CF66_2125 | CF66_7026 | Bifunctional protein. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.622 |
| birA | xthA | CF66_2125 | CF66_5014 | Bifunctional protein. | Exodeoxyribonuclease III. | 0.876 |
| dnaN | mutS | CF66_1102 | CF66_2212 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.998 |
| dnaN | mutY | CF66_1102 | CF66_7027 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.714 |
| dnaN | polA | CF66_1102 | CF66_1032 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I. | 0.999 |
| dnaN | xthA | CF66_1102 | CF66_5014 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exodeoxyribonuclease III. | 0.959 |
| hemN-2 | mutY | CF66_7025 | CF66_7027 | Oxidoreductase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.410 |
| mutS | dnaN | CF66_2212 | CF66_1102 | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.998 |
| mutS | mutY | CF66_2212 | CF66_7027 | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.416 |
| mutS | polA | CF66_2212 | CF66_1032 | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | DNA polymerase I. | 0.995 |
| mutY | CF66_7028 | CF66_7027 | CF66_7028 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Fe(2+)-trafficking protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | 0.735 |
| mutY | birA | CF66_7027 | CF66_2125 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Bifunctional protein. | 0.586 |
| mutY | dnaN | CF66_7027 | CF66_1102 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.714 |
| mutY | hemN-2 | CF66_7027 | CF66_7025 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Oxidoreductase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.410 |
| mutY | mutS | CF66_7027 | CF66_2212 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.416 |
| mutY | nth | CF66_7027 | CF66_2320 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.676 |
| mutY | polA | CF66_7027 | CF66_1032 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | DNA polymerase I. | 0.467 |