| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| carA | carB | CF66_2249 | CF66_2250 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | 0.999 |
| carA | guaA | CF66_2249 | CF66_9008 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.468 |
| carA | purF | CF66_2249 | CF66_7110 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.782 |
| carA | purL | CF66_2249 | CF66_0105 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.992 |
| carA | pyrB | CF66_2249 | CF66_3023 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.998 |
| carA | pyrC | CF66_2249 | CF66_7103 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. | 0.567 |
| carA | pyrD | CF66_2249 | CF66_2379 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.927 |
| carA | pyrE | CF66_2249 | CF66_3011 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.923 |
| carA | pyrI | CF66_2249 | CF66_3024 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Aspartate carbamoyltransferase regulatory chain; Involved in allosteric regulation of aspartate carbamoyltransferase. | 0.862 |
| carB | carA | CF66_2250 | CF66_2249 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | 0.999 |
| carB | guaA | CF66_2250 | CF66_9008 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.828 |
| carB | metG | CF66_2250 | CF66_2294 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.481 |
| carB | purF | CF66_2250 | CF66_7110 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.855 |
| carB | purL | CF66_2250 | CF66_0105 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.911 |
| carB | pyrB | CF66_2250 | CF66_3023 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.998 |
| carB | pyrC | CF66_2250 | CF66_7103 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. | 0.789 |
| carB | pyrD | CF66_2250 | CF66_2379 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.969 |
| carB | pyrE | CF66_2250 | CF66_3011 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.948 |
| carB | pyrI | CF66_2250 | CF66_3024 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Aspartate carbamoyltransferase regulatory chain; Involved in allosteric regulation of aspartate carbamoyltransferase. | 0.899 |
| guaA | carA | CF66_9008 | CF66_2249 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | 0.468 |