STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
M6VBX3_9LEPTUnannotated protein; Belongs to the small heat shock protein (HSP20) family. (142 aa)    
Predicted Functional Partners:
clpA
Unannotated protein; Belongs to the ClpA/ClpB family.
  
 
 0.717
clpC
Unannotated protein; Belongs to the ClpA/ClpB family.
  
 
 0.717
clpB
Unannotated protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
 
 0.717
M6VXC9_9LEPT
Unannotated protein.
   
 
 0.716
dnaK
Unannotated protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.647
M6V459_9LEPT
Unannotated protein; Belongs to the small heat shock protein (HSP20) family.
 
    
0.550
grpE
Unannotated protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depe [...]
  
  
 0.541
M6VBW1_9LEPT
Unannotated protein.
  
 
 0.526
M6V499_9LEPT
Unannotated protein.
  
 
 0.526
hslV
Unannotated protein; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
   
  
 0.522
Your Current Organism:
Leptospira noguchii
NCBI taxonomy Id: 28182
Other names: ATCC 43288, DSM 21520, L. noguchii, strain CZ 214
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.