STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
M6V499_9LEPTUnannotated protein. (607 aa)    
Predicted Functional Partners:
dnaK
Unannotated protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.992
M6VJC5_9LEPT
Unannotated protein.
    
 0.958
M6V5U3_9LEPT
Unannotated protein.
  
 0.952
M6VAU7_9LEPT
Unannotated protein.
   
 0.948
groL
Unannotated protein; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.921
M6VCW5_9LEPT
Unannotated protein.
  
 0.902
dnaJ
Unannotated protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...]
  
 0.902
M6VHN1_9LEPT
Unannotated protein.
  
 0.902
M6V5J1_9LEPT
Unannotated protein.
  
 0.902
M6VDM7_9LEPT
Unannotated protein.
  
 0.902
Your Current Organism:
Leptospira noguchii
NCBI taxonomy Id: 28182
Other names: ATCC 43288, DSM 21520, L. noguchii, strain CZ 214
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