node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CEN34753.1 | CEN34760.1 | CCYN74_110023 | CCYN74_110025 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Putative Rhomboid protease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.676 |
CEN34753.1 | mutL | CCYN74_110023 | CCYN74_110024 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.691 |
CEN34760.1 | CEN34753.1 | CCYN74_110025 | CCYN74_110023 | Putative Rhomboid protease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.676 |
CEN34760.1 | CEN34823.1 | CCYN74_110025 | CCYN74_110045 | Putative Rhomboid protease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative Rhomboid protease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.755 |
CEN34760.1 | CEN36763.1 | CCYN74_110025 | CCYN74_200004 | Putative Rhomboid protease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Serine hydrolase. | 0.638 |
CEN34760.1 | CEN42104.1 | CCYN74_110025 | CCYN74_90066 | Putative Rhomboid protease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | N-acetylmuramoyl-L-alanine amidase. | 0.602 |
CEN34760.1 | clpB | CCYN74_110025 | CCYN74_90029 | Putative Rhomboid protease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Protein disaggregation chaperone; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.584 |
CEN34760.1 | clpX | CCYN74_110025 | CCYN74_90006 | Putative Rhomboid protease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | ATPase and specificity subunit of ClpX-ClpP ATP-dependent serine protease; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.561 |
CEN34760.1 | ftsH | CCYN74_110025 | CCYN74_630003 | Putative Rhomboid protease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | ATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.703 |
CEN34760.1 | lon | CCYN74_110025 | CCYN74_510012 | Putative Rhomboid protease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.584 |
CEN34760.1 | mutL | CCYN74_110025 | CCYN74_110024 | Putative Rhomboid protease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.809 |
CEN34760.1 | tatA-2 | CCYN74_110025 | CCYN74_10185 | Putative Rhomboid protease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Sec-independent protein translocase protein TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.560 |
CEN34823.1 | CEN34760.1 | CCYN74_110045 | CCYN74_110025 | Putative Rhomboid protease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative Rhomboid protease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.755 |
CEN34823.1 | CEN36763.1 | CCYN74_110045 | CCYN74_200004 | Putative Rhomboid protease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Serine hydrolase. | 0.432 |
CEN34823.1 | CEN42104.1 | CCYN74_110045 | CCYN74_90066 | Putative Rhomboid protease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | N-acetylmuramoyl-L-alanine amidase. | 0.546 |
CEN34823.1 | ftsH | CCYN74_110045 | CCYN74_630003 | Putative Rhomboid protease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | ATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.549 |
CEN34823.1 | tatA-2 | CCYN74_110045 | CCYN74_10185 | Putative Rhomboid protease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Sec-independent protein translocase protein TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.490 |
CEN36763.1 | CEN34760.1 | CCYN74_200004 | CCYN74_110025 | Serine hydrolase. | Putative Rhomboid protease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.638 |
CEN36763.1 | CEN34823.1 | CCYN74_200004 | CCYN74_110045 | Serine hydrolase. | Putative Rhomboid protease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.432 |
CEN36763.1 | clpB | CCYN74_200004 | CCYN74_90029 | Serine hydrolase. | Protein disaggregation chaperone; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.561 |