STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAHFumarylacetoacetase. (431 aa)    
Predicted Functional Partners:
fumC
Fumarate hydratase (fumarase C),aerobic Class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
 0.832
SdhA
Succinate dehydrogenase flavoprotein subunit.
  
 
  0.824
CEN33983.1
Succinate dehydrogenase iron-sulfur subunit.
  
 
  0.810
CEN33992.1
Succinate dehydrogenase (Or fumarate reductase) cytochrome b subunit, b558 family.
    
  0.804
CEN41510.1
Ring-1,2-phenylacetyl-CoA epoxidase subunit PaaE.
  
  
 0.637
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
    0.632
CEN36562.1
Hypothetical protein; No homology to any previously reported sequences.
       0.561
CEN36559.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.539
CEN40606.1
Exported hypothetical protein; No homology to any previously reported sequences.
  
     0.497
nadD
Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
       0.487
Your Current Organism:
Capnocytophaga cynodegmi
NCBI taxonomy Id: 28189
Other names: ATCC 49044, C. cynodegmi, CCUG 24742, CDC group DF-2 like, CIP 103937, DSM 19736, LMG 11513, LMG:11513, NCTC 12243, strain E6447
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