STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
purEN5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (159 aa)    
Predicted Functional Partners:
purK
AIR carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
 
 0.999
purL
Putative phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
  
  
 0.999
purD
Phosphoribosylamine--glycine ligase; Belongs to the GARS family.
  
 0.994
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family.
 
 
 0.983
purH
Bifunctional purine biosynthesis protein PurH (Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase).
 
  
 0.924
CEN38086.1
GAR transformylase.
 
  
 0.910
CEN38110.1
Glutamine phosphoribosylpyrophosphate amidotransferase.
 
  
 0.842
purM
Phosphoribosylformylglycinamidine cyclo-ligase.
 
  
 0.842
purB
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
  
 0.803
guaA
GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP.
     
 0.730
Your Current Organism:
Capnocytophaga cynodegmi
NCBI taxonomy Id: 28189
Other names: ATCC 49044, C. cynodegmi, CCUG 24742, CDC group DF-2 like, CIP 103937, DSM 19736, LMG 11513, LMG:11513, NCTC 12243, strain E6447
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