Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CEN36912.1Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the Dps family. (159 aa)    
Predicted Functional Partners:
CEN34869.1
ATP-dependent Clp protease adaptor protein ClpS; Belongs to the ClpS family.
   
 
 0.840
silP
Silver exporting P-type ATPase.
  
  
 0.614
RaiA
Ribosomal subunit interface protein.
  
    0.580
CEN36915.1
Conserved membrane hypothetical protein; Homologs of previously reported genes of unknown function.
       0.499
CEN36919.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.499
msrAB
Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
  
 0.458
tgt
tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...]
       0.457
oxyR
LysR substrate binding domain protein; Belongs to the LysR transcriptional regulatory family.
 
   
 0.443
CEN36051.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
  
 0.436
CEN36909.1
PAS domain S-box protein.
  
    0.426
Your Current Organism:
Capnocytophaga cynodegmi
NCBI taxonomy Id: 28189
Other names: ATCC 49044, C. cynodegmi, CCUG 24742, CDC group DF-2 like, CIP 103937, DSM 19736, LMG 11513, LMG:11513, NCTC 12243, strain E6447
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