Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CEN36915.1Conserved membrane hypothetical protein; Homologs of previously reported genes of unknown function. (359 aa)    
Predicted Functional Partners:
lptB
Putative lipopolysaccharide transport protein B: ATP-binding component of ABC superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
 
 
 0.973
CEN36785.1
Conserved membrane hypothetical protein; Homologs of previously reported genes of unknown function.
  
 
 
0.860
tgt
tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...]
  
  
 0.776
CEN36919.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.773
BamA
Outer membrane protein assembly complex, YaeT protein.
 
     0.683
CEN34106.1
Conserved membrane hypothetical protein; Homologs of previously reported genes of unknown function.
  
 
 0.562
CEN37151.1
Putative Conserved Non-specific serine/threonine protein kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
     0.562
CEN34744.1
Chaperone protein skp.
  
     0.558
CEN34837.1
Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function.
 
     0.530
lpxC/fabZ
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily.
 
    0.525
Your Current Organism:
Capnocytophaga cynodegmi
NCBI taxonomy Id: 28189
Other names: ATCC 49044, C. cynodegmi, CCUG 24742, CDC group DF-2 like, CIP 103937, DSM 19736, LMG 11513, LMG:11513, NCTC 12243, strain E6447
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