Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RfbDSpore coat polysaccharide biosynthesis protein spsK; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (280 aa)    
Predicted Functional Partners:
rmlC
dTDP-4-deoxyrhamnose-3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
 
 0.999
rmlB
dTDP-glucose 4,6 dehydratase, NAD(P)-binding; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
 
 
 0.987
rmlA
dTDP-glucose pyrophosphorylase (glucose-1-phosphate thymidylyltransferase); Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
 
  
 0.941
CEN37850.1
Glycosyltransferase, group 2 family protein.
 
  
 0.722
CEN37865.1
Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function.
       0.689
CEN34591.1
Glycosyltransferase, group 2 family protein.
 
  
 0.641
CEN37870.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.637
CEN35932.1
Putative UDP-GlcNAc-4,6-dehydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
  
 0.463
CEN37805.1
NAD dependent epimerase/dehydratase family protein.
 
 
 0.448
pglC
Undecaprenyl phosphate N,N'-diacetylbacillosamine 1-phosphate transferase.
  
  
 0.429
Your Current Organism:
Capnocytophaga cynodegmi
NCBI taxonomy Id: 28189
Other names: ATCC 49044, C. cynodegmi, CCUG 24742, CDC group DF-2 like, CIP 103937, DSM 19736, LMG 11513, LMG:11513, NCTC 12243, strain E6447
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