node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CEN33923.1 | CEN33925.1 | CCYN74_10195 | CCYN74_10196 | Putative homoserine O-acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Homoserine dehydrogenase. | 0.999 |
CEN33923.1 | CEN39785.1 | CCYN74_10195 | CCYN74_40066 | Putative homoserine O-acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | (P)ppGpp synthetase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.436 |
CEN33923.1 | guaB | CCYN74_10195 | CCYN74_270023 | Putative homoserine O-acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | IMP dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.587 |
CEN33923.1 | ribBA | CCYN74_10195 | CCYN74_40025 | Putative homoserine O-acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Riboflavin biosynthesis protein RibBA (Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.810 |
CEN33923.1 | ribD | CCYN74_10195 | CCYN74_100059 | Putative homoserine O-acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.736 |
CEN33925.1 | CEN33923.1 | CCYN74_10196 | CCYN74_10195 | Homoserine dehydrogenase. | Putative homoserine O-acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.999 |
CEN33925.1 | CEN39785.1 | CCYN74_10196 | CCYN74_40066 | Homoserine dehydrogenase. | (P)ppGpp synthetase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.436 |
CEN33925.1 | guaB | CCYN74_10196 | CCYN74_270023 | Homoserine dehydrogenase. | IMP dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.587 |
CEN33925.1 | ribBA | CCYN74_10196 | CCYN74_40025 | Homoserine dehydrogenase. | Riboflavin biosynthesis protein RibBA (Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.810 |
CEN33925.1 | ribD | CCYN74_10196 | CCYN74_100059 | Homoserine dehydrogenase. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.736 |
CEN39785.1 | CEN33923.1 | CCYN74_40066 | CCYN74_10195 | (P)ppGpp synthetase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Putative homoserine O-acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.436 |
CEN39785.1 | CEN33925.1 | CCYN74_40066 | CCYN74_10196 | (P)ppGpp synthetase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Homoserine dehydrogenase. | 0.436 |
CEN39785.1 | folE | CCYN74_40066 | CCYN74_100064 | (P)ppGpp synthetase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | GTP cyclohydrolase 1. | 0.800 |
CEN39785.1 | guaB | CCYN74_40066 | CCYN74_270023 | (P)ppGpp synthetase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | IMP dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.413 |
CEN39785.1 | ndk | CCYN74_40066 | CCYN74_10041 | (P)ppGpp synthetase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.917 |
CEN39785.1 | ribBA | CCYN74_40066 | CCYN74_40025 | (P)ppGpp synthetase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Riboflavin biosynthesis protein RibBA (Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.831 |
NusB | ribBA | CCYN74_200018 | CCYN74_40025 | N utilization substance protein B-like protein; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | Riboflavin biosynthesis protein RibBA (Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.815 |
NusB | ribD | CCYN74_200018 | CCYN74_100059 | N utilization substance protein B-like protein; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.770 |
NusB | ribH | CCYN74_200018 | CCYN74_440011 | N utilization substance protein B-like protein; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.730 |
folE | CEN39785.1 | CCYN74_100064 | CCYN74_40066 | GTP cyclohydrolase 1. | (P)ppGpp synthetase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.800 |