STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A267E5Z3HMG box domain-containing protein. (924 aa)    
Predicted Functional Partners:
A0A267FEH0
Uncharacterized protein; Belongs to the actin family.
   
 0.990
A0A267G297
Uncharacterized protein; Belongs to the actin family.
   
 0.990
A0A267GP49
Uncharacterized protein; Belongs to the actin family.
   
 0.990
A0A267DQU9
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.981
A0A267FZU4
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.981
A0A267EGT4
Histone H2A; Belongs to the histone H2A family.
   
 0.978
A0A267FLW0
Histone H2A; Belongs to the histone H2A family.
   
 0.978
A0A267GYF0
Histone H2A; Belongs to the histone H2A family.
   
 0.978
A0A1I8GFC5
Uncharacterized protein.
   
 
 0.976
A0A1I8HG17
Uncharacterized protein.
   
 
 0.976
Your Current Organism:
Macrostomum lignano
NCBI taxonomy Id: 282301
Other names: M. lignano
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.