STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A267ERT2DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2375 aa)    
Predicted Functional Partners:
A0A267F190
DNA helicase; Belongs to the MCM family.
   
 0.998
A0A1I8HDS5
DNA helicase; Belongs to the MCM family.
   
 0.997
A0A267DNN9
Uncharacterized protein.
   
 0.997
A0A267F884
DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.
   
 0.997
A0A267GXN1
Uncharacterized protein.
   
 0.997
A0A267FJ18
Uncharacterized protein.
   
 0.996
A0A1I8HHV3
MCM domain-containing protein; Belongs to the MCM family.
   
 0.995
A0A267E1K5
MCM domain-containing protein; Belongs to the MCM family.
   
 0.995
A0A267GTN3
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.994
A0A267F5Q8
DNA helicase; Belongs to the MCM family.
   
 0.993
Your Current Organism:
Macrostomum lignano
NCBI taxonomy Id: 282301
Other names: M. lignano
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.