STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A267EUV1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (373 aa)    
Predicted Functional Partners:
A0A267EFD1
Homeobox domain-containing protein.
   
 
 0.965
A0A267EHH5
Homeobox domain-containing protein.
   
 
 0.965
A0A267EU00
Homeobox domain-containing protein.
   
 
 0.965
A0A267GMT1
Homeobox domain-containing protein.
   
 
 0.965
A0A1I8IVP8
Homeobox domain-containing protein.
   
 
 0.942
A0A267DA39
Homeobox domain-containing protein.
   
 
 0.942
A0A267GV90
Homeobox domain-containing protein.
   
 
 0.942
A0A267DQU9
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
  0.687
A0A267FZU4
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
  0.653
A0A267DU94
Mre11_DNA_bind domain-containing protein; Belongs to the MRE11/RAD32 family.
   
 
  0.622
Your Current Organism:
Macrostomum lignano
NCBI taxonomy Id: 282301
Other names: M. lignano
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.