STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A267GLP5Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (195 aa)    
Predicted Functional Partners:
A0A267DY24
Uncharacterized protein.
    
 0.967
A0A267DY33
Uncharacterized protein.
    
 0.967
A0A267FA46
Uncharacterized protein.
    
 0.967
A0A1I8GCI0
Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
   
 0.957
A0A267FIQ2
Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
   
 0.957
A0A267FNV5
Guanylate kinase-like domain-containing protein.
  
 
 0.952
A0A1I8H8K4
Uncharacterized protein.
  
 
 0.926
A0A267E9B6
GMPS ATP-PPase domain-containing protein.
  
 
 0.926
A0A267FJ79
Uncharacterized protein.
  
 
 0.926
A0A267DQ43
Pribosyltran domain-containing protein.
  
 0.918
Your Current Organism:
Macrostomum lignano
NCBI taxonomy Id: 282301
Other names: M. lignano
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