STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOM00202.1Cytochrome C biogenesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (265 aa)    
Predicted Functional Partners:
dsbC
Protein-disulfide isomerase; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.
 
     0.675
AOM00201.1
Magnesium/cobalt efflux protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.637
dsbA
Disulfide bond formation protein DsbA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.592
AOM02582.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.544
holA
DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.497
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...]
       0.491
rimM
Ribosome maturation factor RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.
 
     0.463
zipA
Hypothetical protein; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
  
     0.460
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
     0.449
glnE
Bifunctional glutamine synthetase adenylyltransferase/deadenyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of [...]
  
     0.437
Your Current Organism:
Cobetia marina
NCBI taxonomy Id: 28258
Other names: ATCC 25374, ATCC 29686 [[Halomonas halodurans]], Arthrobacter marinus, C. marina, CCUG 49558, CECT 4278, CIP 104765, DSM 4741, DSM 5160 [[Halomonas halodurans]], Deleya marina, Halomonas halodurans, Halomonas marina, IFO 15607 [[Halomonas halodurans]], JCM 21022, LMG 2217, LMG:2217, NBRC 102605, NBRC 15607 [[Halomonas halodurans]], Pseudomonas halodurans, Pseudomonas marina, strain 219
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