Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AOM01254.1Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (501 aa)    
Predicted Functional Partners:
sdhA
Succinate dehydrogenase flavoprotein subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
  
 
 0.996
AOM02272.1
Succinate dehydrogenase iron-sulfur subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.994
sdhC
Succinate dehydrogenase, cytochrome b556 subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.983
sdhD
Succinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH).
  
 
 0.979
aspA
Aspartate ammonia-lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 
 0.976
prpC
2-methylcitrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family.
  
 
 0.974
gltA
Citrate (Si)-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family.
  
 
 0.974
icd
Pseudouridine synthase; Incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.972
AOM00292.1
Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.969
maeA
Malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.965
Your Current Organism:
Cobetia marina
NCBI taxonomy Id: 28258
Other names: ATCC 25374, ATCC 29686 [[Halomonas halodurans]], Arthrobacter marinus, C. marina, CCUG 49558, CECT 4278, CIP 104765, DSM 4741, DSM 5160 [[Halomonas halodurans]], Deleya marina, Halomonas halodurans, Halomonas marina, IFO 15607 [[Halomonas halodurans]], JCM 21022, LMG 2217, LMG:2217, NBRC 102605, NBRC 15607 [[Halomonas halodurans]], Pseudomonas halodurans, Pseudomonas marina, strain 219
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