Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ARM74652.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (742 aa)    
Predicted Functional Partners:
ARM75771.1
S2P metalloprotease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.523
ARM75214.1
Quinol oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.520
ARM75215.1
MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.485
hisS
histidine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
    0.452
rpl13
50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
    0.447
ARM76616.1
Amino acid permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.429
ARM76054.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.422
thiI
tRNA 4-thiouridine(8) synthase ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
  
 0.421
Your Current Organism:
Acidianus manzaensis
NCBI taxonomy Id: 282676
Other names: A. manzaensis, NBRC 100595, strain NA-1
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