Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARM74879.1DHH family phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)    
Predicted Functional Partners:
ARM74878.1
Isochorismatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.901
ARM74876.1
Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.754
nfi
Endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
       0.754
ARM74875.1
KaiC domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.642
ARM75972.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.602
ARM75155.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.576
ARM75134.1
Flagellar assembly protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.562
ARM74880.1
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
       0.555
ARM76504.1
Carboxylate--amine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.550
ARM75859.1
HIT family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.549
Your Current Organism:
Acidianus manzaensis
NCBI taxonomy Id: 282676
Other names: A. manzaensis, NBRC 100595, strain NA-1
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.