Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ARM74880.1Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. (215 aa)    
Predicted Functional Partners:
ARM75978.1
Glutaredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.829
ARM76660.1
Glutaredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.829
ARM77029.1
Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.825
ARM76457.1
Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.825
ARM74914.1
Thioredoxin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.759
ARM75028.1
ferredoxin--NADP(+) reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.759
ARM75109.1
Thioredoxin-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.759
ARM75009.1
Transcriptional repressor; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.710
ARM74878.1
Isochorismatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.673
mre11
Metallophosphoesterase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family.
  
 
 0.639
Your Current Organism:
Acidianus manzaensis
NCBI taxonomy Id: 282676
Other names: A. manzaensis, NBRC 100595, strain NA-1
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