Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ARM74984.1Aspartate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (356 aa)    
Predicted Functional Partners:
ARM76540.1
Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family.
 
 
 0.978
sucD
succinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.925
ARM77184.1
succinate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.922
ARM76241.1
Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.921
ARM75444.1
Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.918
ARM75535.1
Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.918
ARM74891.1
Pyruvate carboxylase subunit A; Catalyzes the ATP-dependent carboxylation of a covalently attached biotin and the transfer of the carboxyl group to pyruvate forming oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.915
ARM74889.1
methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.911
ARM75103.1
methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.909
ARM74890.1
acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.908
Your Current Organism:
Acidianus manzaensis
NCBI taxonomy Id: 282676
Other names: A. manzaensis, NBRC 100595, strain NA-1
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