Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ARM75027.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (158 aa)    
Predicted Functional Partners:
rnp4
RNAse P, Rpr2/Rpp21 subunit; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
 
     0.971
ARM75026.1
RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.927
nep1
16S rRNA methyltransferase; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.
 
     0.761
tfe
Transcription factor E; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems [...]
  
     0.668
ARM75925.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.606
tiaS
tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
  
    0.528
ARM77116.1
Multidrug MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.515
hjc
Endonuclease; A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products; Belongs to the Holliday junction resolvase Hjc family.
  
     0.498
ARM77149.1
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.495
ARM75252.1
protein-L-isoaspartate O-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.492
Your Current Organism:
Acidianus manzaensis
NCBI taxonomy Id: 282676
Other names: A. manzaensis, NBRC 100595, strain NA-1
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