Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ARM75083.1DNA polymerase IV; Dpo4; involved in translesion DNA polymerization; belongs to Y family of polymerases; does not contain proofreading function; Derived by automated computational analysis using gene prediction method: Protein Homology. (353 aa)    
Predicted Functional Partners:
pcn-3
DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
  
 0.972
ARM75765.1
DNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.971
ARM76327.1
Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein has been shown to be aphidicolin resistant and stable up to 80#C; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.971
pcn
DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
  
 0.968
pcn-2
DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family.
  
 0.967
ARM75082.1
Sugar kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.954
rpl40e
50S ribosomal protein L40e; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL40 family.
  
 
 0.951
ARM75690.1
AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.899
radA
DNA repair and recombination protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
  
 0.899
ARM75250.1
DNA polymerase II; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.893
Your Current Organism:
Acidianus manzaensis
NCBI taxonomy Id: 282676
Other names: A. manzaensis, NBRC 100595, strain NA-1
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