Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARM75138.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (98 aa)    
Predicted Functional Partners:
ARM75137.1
NMD protein affecting ribosome stability and mRNA decay; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.955
eif2b
Translation initiation factor IF-2 subunit beta; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family.
       0.949
ARM75135.1
GTP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.944
ARM75136.1
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
       0.944
ARM75140.1
2-methylthioadenine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.812
eif1a
Translation initiation factor eIF-1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
 
     0.806
ARM75144.1
RNA-processing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.799
ARM75143.1
Serine protein kinase RIO; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.784
ARM75683.1
Cell division control protein Cdc6; Involved in regulation of DNA replication.
  
     0.616
ARM76543.1
Hypothetical protein; Involved in DNA damage repair.
  
     0.581
Your Current Organism:
Acidianus manzaensis
NCBI taxonomy Id: 282676
Other names: A. manzaensis, NBRC 100595, strain NA-1
Server load: medium (42%) [HD]