Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ARM75157.1Disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)    
Predicted Functional Partners:
ARM75159.1
Succinate dehydrogenase flavoprotein subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.999
ARM75156.1
Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.995
ARM75158.1
Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.993
ARM76769.1
Pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.991
ARM75321.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.971
ARM74841.1
Arylmalonate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.921
ARM75374.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
  
  0.914
ARM74834.1
Fumarate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.907
sucD
succinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.905
ARM77184.1
succinate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.903
Your Current Organism:
Acidianus manzaensis
NCBI taxonomy Id: 282676
Other names: A. manzaensis, NBRC 100595, strain NA-1
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