Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
prf1Peptide chain release factor 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. (358 aa)    
Predicted Functional Partners:
ARM77111.1
Ribosome biogenesis/translation initiation ATPase RLI; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.987
tuf
Translation elongation factor EF-1 subunit alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
  
 0.984
rpl15e
50S ribosomal protein L15e; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL15 family.
 
 0.971
rpl10
50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
  
 0.958
rps15
30S ribosomal protein S15; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.957
rpl24
50S ribosomal protein L24; Located at the polypeptide exit tunnel on the outside of the subunit.
  
  0.956
rps17
30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
  
  0.953
rps3ae
30S ribosomal protein S3ae; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eS1 family.
  
  0.946
rpl32e
50S ribosomal protein L32e; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL32 family.
  
  0.943
rps4e
30S ribosomal protein S4e; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eS4 family.
  
  0.942
Your Current Organism:
Acidianus manzaensis
NCBI taxonomy Id: 282676
Other names: A. manzaensis, NBRC 100595, strain NA-1
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