Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARM75320.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (120 aa)    
Predicted Functional Partners:
ARM75159.1
Succinate dehydrogenase flavoprotein subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.998
ARM75319.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 
 0.997
ARM75321.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.997
ARM75158.1
Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.987
ARM77153.1
NADH dehydrogenase subunit D; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the complex I 49 kDa subunit family.
  
 
 0.958
ARM77184.1
succinate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.936
sucD
succinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
  
 0.912
ARM76333.1
NADH-quinone oxidoreductase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.906
ARM76334.1
NADH-quinone oxidoreductase subunit C; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.873
ARM75705.1
NADH-quinone oxidoreductase subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the complex I 20 kDa subunit family.
  
  
 0.848
Your Current Organism:
Acidianus manzaensis
NCBI taxonomy Id: 282676
Other names: A. manzaensis, NBRC 100595, strain NA-1
Server load: medium (52%) [HD]