Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ARM75627.1Exopolyphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (418 aa)    
Predicted Functional Partners:
ARM75628.1
Phosphohistidine phosphatase SixA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
   0.961
ARM75625.1
Thymidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.950
tmk
dTMP kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.950
ARM75624.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.940
ARM75629.1
Acetolactate synthase catalytic subunit; Catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.614
ARM74887.1
Anion permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.579
ppa
Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
     
 0.476
ARM75030.1
NAD(+) kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.459
ARM76538.1
Menaquinone biosynthesis decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.422
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
  
  
 0.405
Your Current Organism:
Acidianus manzaensis
NCBI taxonomy Id: 282676
Other names: A. manzaensis, NBRC 100595, strain NA-1
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