Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
ARM75698.1tRNA(Met) cytidine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (736 aa)    
Predicted Functional Partners:
ARM77175.1
C/D box methylation guide ribonucleoprotein complex aNOP56 subunit; Functions along with aFIB and aL7a; guides 2'-O-methylation of ribose to specific sites in RNAs; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.958
rtcA
RNA 3'-phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
   
 
 0.921
ARM75144.1
RNA-processing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.915
ARM75829.1
tRNA pseudouridine synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.902
nep1
16S rRNA methyltransferase; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.
  
 
 0.899
ARM75828.1
tRNA pseudouridine(55) synthase TruB; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.891
ARM76268.1
GTP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.878
ARM75684.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.876
rpl7ae
50S ribosomal protein L7ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
 
 
 0.869
rps15
30S ribosomal protein S15; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.818
Your Current Organism:
Acidianus manzaensis
NCBI taxonomy Id: 282676
Other names: A. manzaensis, NBRC 100595, strain NA-1
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