Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ARM75731.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)    
Predicted Functional Partners:
ARM74868.1
Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.971
ARM75732.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.950
ARM75733.1
Glycosyl transferase family 2; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.941
ARM75040.1
Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.917
ARM75734.1
ATP-dependent helicase; Hel112; monomeric form of the enzyme from Sulfolobus shows 3'-5' ATP-dependent helicase activity; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.860
fen
Flap endonuclease-1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...]
  
 
 0.832
ARM77116.1
Multidrug MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.761
trpA
Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
  
 0.685
ARM76412.1
dephospho-CoA kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.666
ARM75083.1
DNA polymerase IV; Dpo4; involved in translesion DNA polymerization; belongs to Y family of polymerases; does not contain proofreading function; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.600
Your Current Organism:
Acidianus manzaensis
NCBI taxonomy Id: 282676
Other names: A. manzaensis, NBRC 100595, strain NA-1
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