Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ARM75792.1Kae1-associated kinase Bud32; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)    
Predicted Functional Partners:
kae1
tRNA threonylcarbamoyladenosine biosynthesis protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37; Belongs to the KAE1 / TsaD family.
  
 0.998
rps24e
30S ribosomal protein S24e; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eS24 family.
 
    0.971
ARM75793.1
Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HAM1 NTPase family.
     
 0.957
rps27ae
30S ribosomal protein S27ae; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eS31 family.
       0.947
thi4
Ribose 1,5-bisphosphate isomerase; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
       0.918
rps15
30S ribosomal protein S15; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.819
ARM75143.1
Serine protein kinase RIO; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.776
ARM76414.1
Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.768
ARM76465.1
Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.763
infB
Translation initiation factor IF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.
 
  
 0.760
Your Current Organism:
Acidianus manzaensis
NCBI taxonomy Id: 282676
Other names: A. manzaensis, NBRC 100595, strain NA-1
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