Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
ARM75820.13,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the formation of 3,4-dihydroxy 2-butanone 4-phosphate from ribulose 5-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa)    
Predicted Functional Partners:
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
 
 
 0.999
ARM75821.1
Riboflavin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.987
ARM75850.1
2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.968
gch3
Hypothetical protein; Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity; Belongs to the archaeal-type GTP cyclohydrolase family.
 
     0.963
ARM75824.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.963
rps2
30S ribosomal protein S2; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS2 family.
  
  
 0.679
ARM75819.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.664
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
 
  
 0.630
ARM75852.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.579
ARM77178.1
Cytidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.551
Your Current Organism:
Acidianus manzaensis
NCBI taxonomy Id: 282676
Other names: A. manzaensis, NBRC 100595, strain NA-1
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