Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ARM75821.1Riboflavin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (155 aa)    
Predicted Functional Partners:
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
 
  
  0.997
ARM75820.1
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the formation of 3,4-dihydroxy 2-butanone 4-phosphate from ribulose 5-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.987
ARM75824.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.973
gch3
Hypothetical protein; Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity; Belongs to the archaeal-type GTP cyclohydrolase family.
 
     0.959
ribK
Riboflavin kinase; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family.
    
  0.928
ARM75819.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.664
ARM75137.1
NMD protein affecting ribosome stability and mRNA decay; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.620
ARM75818.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.528
ARM75155.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.492
ARM77178.1
Cytidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.491
Your Current Organism:
Acidianus manzaensis
NCBI taxonomy Id: 282676
Other names: A. manzaensis, NBRC 100595, strain NA-1
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