Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
ARM75827.1Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (913 aa)    
Predicted Functional Partners:
ARM75979.1
CopG family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.813
ARM75826.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.794
ARM74875.1
KaiC domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.776
ARM76914.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.763
ARM77177.1
Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.712
pcn-2
DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family.
       0.619
ARM77104.1
RNA polymerase Rpo13; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.617
rpl14e
50S ribosomal protein L14e; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL14 family.
       0.578
ARM75828.1
tRNA pseudouridine(55) synthase TruB; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.555
nfi
Endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
      
 0.523
Your Current Organism:
Acidianus manzaensis
NCBI taxonomy Id: 282676
Other names: A. manzaensis, NBRC 100595, strain NA-1
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